Genetic polymorphisms of IL1RN were associated with lumbar disk herniation risk in a Chinese Han population
نویسندگان
چکیده
منابع مشابه
Genetic variations in IL1A and IL1RN are associated with the risk of preeclampsia in Chinese Han population
Preeclampsia (PE) is an excessive systemic inflammation response with dysfunction of endothelial. Our study was to investigate the association between genetic variations in IL-1 and the susceptibility to PE in Chinese Han population. 402 PE patients and 554 normal pregnant women of third trimester were enrolled. The polymorphisms of rs315952 in IL1RN and rs17561 in IL1A were genotyped by TaqMan...
متن کاملInterleukin-1β-31C/T and -511T/C Polymorphisms Were Associated with Preeclampsia in Chinese Han Population
OBJECTIVE The purpose of our study is to investigate the relationship between IL-1β -31C/T (rs1143627) and -511T/C (rs16944) polymorphisms and the preeclampsia (PE), and analyze the Linkage disequilibrium (LD) and haplotype frequency of the two polymorphism loci. METHODS Polymorphisms at -31C/T and -511T/C of IL-1β were genotyped with the method of polymerase chain reaction-restriction fragme...
متن کاملassociation between tnfaip3 gene polymorphisms and risk of allergic rhinitis in a chinese han population
tumor necrosis factor alpha-inducible protein 3 (tnfaip3) gene polymorphisms have been reported to be associated with the susceptibility to several immune-related diseases. here we investigated the effect of tnfaip3 gene polymorphisms on the risk of allergic rhinitis (ar) in a chinese han population. the case-control study included 540 ar patients and 524 healthy controls. genotyping for tnfaip...
متن کاملGenetic Polymorphisms in ZFHX3 Are Associated with Atrial Fibrillation in a Chinese Han Population
BACKGROUND The gene zinc finger homeobox 3 (ZFHX3) encodes a transcription factor with cardiac expression and its genetic variants are associated with atrial fibrillation (AF). We aimed to explore the associations between single nucleotide polymorphisms (SNPs) of ZFHX3 and the risk of AF in a Chinese Han population. METHODS We genotyped eight SNPs, including seven potentially functional SNPs ...
متن کاملGenetic polymorphisms in ALDH2 are associated with drug addiction in a Chinese Han population
We investigated the association between single nucleotide polymorphisms (SNPs) in ALDH2, which has been associated with alcohol dependence and several types of diseases, and the risk of drug addiction in a Chinese Han population. In a case-control study that included 692 cases and 700 healthy controls, eight SNPs in ALDH2 were selected and genotyped using the Sequenom MassARRAY platform. Odds r...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Molecular Genetics & Genomic Medicine
سال: 2020
ISSN: 2324-9269,2324-9269
DOI: 10.1002/mgg3.1247